Side Effects Game

About Side Effects Game

Side Effects is a gripping survival-based experimental game that immerses players in a thrilling and suspenseful scenario.

Welcome to Side Effects: A Deadly Game of Survival

Published by itch.io in 2025, Side Effects is an experimental online game that plunges players into a chilling medical trial. Inspired by Buckshot Roulette, this indie prototype presents a psychological challenge where every decision can mean life or death. With only two test subjects and one inevitable survivor, the stakes are high!

Gameplay Mechanics

In Side Effects, players engage in a suspenseful round of pill roulette. Each round begins with a mystery pill that you must ingest. Will it heal you, harm you, or bring unexpected effects? Your choices determine your survival as you manage your tolerance and use limited resources.

Controls are simple and intuitive. Use your mouse to interact with various objects and pills throughout the game. Click to select items, track effects, and make crucial decisions.

Tips for Playing

• Stay Alert: Keep a close eye on your opponent’s moves. Adjust your strategy based on their actions.
• Manage Your Resources: Use items wisely to tip the odds in your favor. Every choice counts!
• Embrace Replayability: With randomized effects each round, no two matches are the same. Experiment with different strategies to find what works best.

Why Play Side Effects?

This game stands out for its unique blend of survival, randomness, and strategy. The minimalist design enhances the eerie atmosphere, immersing players in a bleak medical lab setting. The downloaded version provides smoother visuals and a more stable experience, making it the ideal way to enjoy the game.

Dive into the world of Side Effects today and see if you can be the last one standing!